| Name | Post held |
| Eamon de Valera | Taoiseach (to: 23.6.1959 - resigned) |
| Sean F. Lemass | Tánaiste and Minister for Industry & Commerce |
| Sean MacEntee | Minister for Health, Minister for Social Welfare (from: 27.11.1957) |
| James Ryan | Minister for Finance |
| Frank Aiken | Minister for External Affairs, Minister for Agriculture (from: 20.03.1957 to 16.05.1957 and from: 20.11.1957 to 27.11.1957) |
| Oscar Traynor | Minister for Justice |
| Patrick Smith | Minister for Local Government (to: 27.11.1957) , Minister for Social Welfare (to: 27.11.1957) , Minister for Agriculture (from: 27.11.1957) |
| Erskine Childers | Minister for Lands |
| Jack Lynch | Minister for Education, Minister for the Gaeltacht (to 26.6.57) |
| Neil Blaney | Minister for Posts and Telegraphs (to: 4.12.1957) , Minister for Local Government (from: 27.11.1957) |
| Kevin Boland | Minister for Defence |
| Sean Moylan | Minister for Agriculture (16.05.1957 - 16.11.57 - died) |
| Michael Moran | Minister for Gaeltacht (from 26.6.57) |
| John Ormonde | Minister for Posts and Telegraphs (from: 4 .12.57) |
Single-party Fianna Fáil Government.
Eamonn de Valera retired from politics on 23.6.1959
| Name | Post held |
| Donnchadh O Briain | Parl. Sec. to the Taoiseach and Parl. Sec. to Minister for Defence |
| Patrick Beegan | Parl. Sec. to Minister for Finance (to: 1.2.1958 - died) |
| Michael J. Kennedy | Parl. Sec. to Minister for Social Welfare |
| Gerald Bartley | Parl. Sec. to Minister for Industry and Commerce (to: 24.2.1958) , Parl. Sec. to Minister for Finance (from: 24.2.1958) |
| Michael Hilliard | Parl. Sec. to Minister for Industry and Commerce (from: 24.2.1958) |
Single-party Fianna Fáil Government.
| Name | Post held |
| Eamon de Valera | (Resigned 17.6.59, but continued as Taoiseach until appointment of successor on 23.6.59) |
| Sean F. Lemass | Taoiseach (appointed on 23.6.59) |
| Sean MacEntee | Tánaiste and Minister for Health, Minister for Social Welfare |
| James Ryan | Minister for Finance |
| Frank Aiken | Minister for External Affairs |
| Oscar Traynor | Minister for Justice |
| Patrick Smith | Minister for Agriculture |
| Erskine Childers | Minister for Transport & Power (from 27.7.59) , Minister for Lands (to: 23.7.1959) , Minister without portfolio 24-26.7.59 |
| Michael Moran | Minister for the Gaeltacht (to: 23.7.1959) , Minister for Lands (from: 23.7.1959) |
| Jack Lynch | Minister for Industry & Commerce |
| Neil Blaney | Minister for Local Government |
| Kevin Boland | Minister for Defence |
| Michael Hilliard | Minister for Posts and Telegraphs |
| Patrick J. Hillery | Minister for Education |
| Gerald Bartley | Minister for the Gaeltacht (from: 23.7.1959) |
Single-party Fianna Fáil Government.
Following Eamonn de Valera's retirement from politics, Sean F. Lemass was appointed Taoiseach and Fianna Fáil continued in Government.There was no need for a General Election.
A new Department of Transport and Power was created.
| Name | Post held |
| Donnchadh O Briain | Parl. Sec. to the Taoiseach and Parl. Sec. to Minister for Defence |
| Michael J. Kennedy | Parl. Sec. to Minister for Social Welfare |
| Gerald Bartley | Parl. Sec. to Minister for Finance (to: 23.7.1959 - appointed as member of Govt.) |
| Joseph Brennan | Parl. Sec. to Minister for Finance (from: 27.7.1959) |
| Charles J. Haughey | Parl. Sec. to Minister for Justice |
Single-party Fianna Fáil Government.